Transderma isn't a cosmetics brand — it's a vitamin delivery system, engineered to cross the skin barrier intact and act on the cells that produce collagen, elastin, cellular energy, and renewal. Thirty years of research. Five serums.
Walk down any skincare aisle and read the labels. Between 60% and 90% of most serums and creams is water. The rest is emulsifiers, thickeners, fragrance, and preservatives, ingredients there to hold the formula together, not to do work on your skin.
Transderma was built in the opposite direction. Start with what the skin actually needs (stable, concentrated vitamin actives) and remove everything that isn't doing work. No water, no emulsifiers, no fragrance, no color. The bottle is the formula, and it stays potent from the first drop to the last, with a 2-year shelf life that's rare in skincare.
This is the hard version. The easier one is to add water, lower the active concentration, preserve the water, and charge less. We've turned that down for thirty years.
Skincare you can feel does its work on the surface, which is the reach of nearly every conventional serum. Lasting renewal happens deeper. The diagram below shows where Transderma travels and where most others stop.
The stratum corneum is skin's outer barrier: dead, compacted cells that block most of what we apply. Transderma's waterless formula passes through it within seconds of application. Active vitamins reach the living tissue below intact, with nothing lost to evaporation.
Most serums stop here, deposited among the epidermis's living cells, unable to go further. Transderma contains no water, so every drop holds its full vitamin concentration as it travels. Nothing is diluted along the way; the formula keeps moving toward the dermis.
The dermis is where lasting skin change is actually produced: collagen, elastin, and cellular renewal all begin here. Transderma carries concentrated vitamins directly into this layer, where fibroblasts can put them to work. This is the layer conventional serums rarely reach, and the reason our results show over weeks.
Beneath the dermis sits the subcutaneous layer, fatty tissue that anchors the skin and holds its shape. By this depth, Transderma's vitamins have already been taken up by the dermis above. The tissue here is the structural foundation for the renewal happening in every layer built on top of it.
Three engineering problems separate a conventional serum from Transderma: keeping the vitamins stable, getting them past the skin's surface, and reaching the cells that actually produce the results you're after. Each is hard in isolation. We solved all three.
Vitamins C and A oxidize within days once they meet air or light. Most brands either dilute the actives or add preservatives. We stabilize ours through ingredient architecture instead.
Most serums sit on the stratum corneum and deliver their actives nowhere. Transderma's formulations cross the barrier intact and concentrated, the same principle that makes a nicotine patch work.
Each serum is engineered around one biological system:
Every Transderma serum targets one of five biological systems. Knowing which one is how you build a routine, and why we stopped at five.
Structural proteins that keep skin firm.
Decline with age and UV.
Stimulated by C and A at the fibroblast.
How fast old cells are replaced by new ones.
Slows with age.
Retinol restarts it.
Neutralizes free radicals from UV, pollution, metabolism.
Vitamin C and Resveratrol, two of the most potent topical antioxidants known.
Lipid structure that holds moisture in, irritants out.
Degrades with age, weather, over-washing.
Rebuilt by skin-identical ceramides.
The cell's energy factory.
Output drops with age, and so does collagen, repair, renewal.
PQQ, B vitamins, creatine feed it directly.
Each Transderma serum does one biological job well, with the minimum number of ingredients required to do it. They're designed to be used alone or stacked: a toolkit, not a routine.
Pure 10% L-ascorbic acid. Stimulates collagen synthesis in the fibroblasts, neutralizes free radicals, and lifts pigmentation over time. The industry standard is 20% in water, where it becomes irritating; ours is anhydrous, so 10% is enough.
Retinyl palmitate, which the skin converts to retinol on application. Drives cell turnover; over weeks, softens fine lines and evens out texture and tone. Stabilized with Vitamin E against oxidation. Use at night.
The formula we built around the mitochondria. PQQ, B vitamins, niacinamide, and creatine feed the cell's energy machinery, so when mitochondrial output drops with age, collagen production and repair drop with it. Targets the source rather than the surface.
Six ingredients. Skin-identical lipids and ceramides rebuild the moisture barrier from inside. Most moisturizers are 65–85% water plus alcohol and preservatives, which can dry the skin further. M works at the layer that produces hydration on its own.
Four ingredients. Resveratrol is among the most potent plant-derived antioxidants, effective on acne scarring, uneven pigmentation, and post-inflammatory marks. Works on face, neck, and hands. If the bottle ever darkens, it has oxidized; don't use it. Ours seldom does.
Most premium serums ship in pump-and-pipette bottles, which have air inside. Every pump pulls air in, which oxidizes the actives. That's why your $180 Vitamin C turns orange in three months, and why those bottles need preservatives in the first place.
Transderma bottles are truly airless. Not "less air." None. Once sealed, the bottle cannot be opened and cannot let air in. Without oxidation, the actives stay stable. Without contamination risk, preservatives become unnecessary. The packaging isn't a delivery vehicle. It's part of the formulation.
2-year shelf life. Stable and potent from the first drop to the last.
Lab inspected and approved by Läkemedelsverket (Sweden) and registered under EU Cosmetics Legislation. The chemistry is built on 30+ years of Dr. Klaus Alvin Ronlán's published research at the University of Lund and KTH Stockholm, including over 58 peer-reviewed papers in antioxidant chemistry and transdermal delivery. Read the full story →
The Discovery Kit contains pocket-size versions of all five serums and a printed guide to building your routine. Start there.
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