01
Cellular energy
PQQ and B vitamins support mitochondrial biogenesis and function, literally increasing the energy available to every skin cell.
Cellular Energy · Day
Serum O.
Renews and revitalizes tired-looking skin. Especially formulated for mature skin.
$17530 ml · Day application
The work Energy for the cells that age slowest.
Serum O is our most distinctive formula and our most scientifically differentiated. It targets the mitochondria · the energy factories inside every skin cell · with a blend of PQQ, B vitamins, Vitamin C, niacinamide, and creatine. As mitochondrial output declines with age, so does the cell's capacity to produce collagen, repair damage, and renew. O feeds that system directly.
Most skincare ignores the cellular-energy layer entirely. It's invisible. You can't see a healthy mitochondrion in the mirror. But you can see its absence: slower recovery, lost radiance, skin that looks tired even when you aren't. Serum O is where Transderma stops being skincare and becomes longevity chemistry applied topically.
"Separate from every skincare brand · biology, not cosmetics. Longevity, not illusion."
Particularly suited to mature skin, but appropriate for any skin type that wants a cellular-level boost. Works alongside any other serum in the line; especially powerful stacked with A at night (turnover + energy) or with C by day (collagen + energy).
Ingredients Eight ingredients. All functional.
Unlike our other serums, O is a blend: a deliberate stack of vitamins and cellular-energy molecules, each chosen for a specific mitochondrial or renewal function. Still anhydrous. Still no fragrance, no preservatives. Still stabilized by the airless delivery system.
01
Organic 1,2-Propanediol Delivery vehicle
The same plant-derived solvent used in Serum C. Carries the active stack through the skin barrier intact.
02
L-Ascorbic Acid Vitamin C
Supports collagen synthesis and provides antioxidant defense while amplifying the cellular-energy benefits of the blend.
03
Niacinamide Vitamin B3
A precursor to NAD+, one of the most important molecules in cellular energy metabolism. Also supports barrier function and reduces inflammation.
04
Creatine Cellular energy transporter
The same molecule used by muscle cells to move energy where it's needed. Skin cells use it too, and benefit from direct topical supply.
05
Pyridoxine Cyclic Phosphate Vitamin B6
Supports amino-acid metabolism and the production of neurotransmitters involved in skin signaling. A co-factor in over a hundred cellular reactions.
06
Kinetin Plant cytokinin · Longevity
A plant-derived growth factor studied for its effects on cellular aging. Delays visible signs of senescence in skin cells; reduces oxidative stress markers.
07
Bio-PQQ Pyrroloquinoline Quinone Disodium Salt
The active the serum is named around. PQQ triggers mitochondrial biogenesis (the creation of new mitochondria) in ways few other molecules are known to. Supports cellular energy at the root.
08
Biotin Vitamin B7
A co-factor in energy metabolism and fatty-acid synthesis. Supports the lipid architecture that keeps skin cells functioning properly.
How to use Once or twice daily. Stacks easily.
Apply to clean, dry skin. Allow one to five minutes for the serum to absorb. Layer with Serum M if your skin needs moisture, allow to absorb completely, then continue with your daily routine. Works morning or night.
01
Clean, dry skin
Cleanse and dry. One to two drops across face and neck, before any cream or moisturizer.
02
Allow to absorb
One to five minutes for the serum to sink in fully.
03
Finish with moisture
Finish with Transderma Moisture Serum (M) if needed, or stack with Serum A or C. Let it absorb completely.
04
Continue routine
Once completely absorbed, you can continue with your usual routine.
Best for mature skin. Anyone can benefit from mitochondrial support, but O is particularly valuable for skin over 40 or for anyone who feels their skin has lost its capacity to bounce back.
What it does
Four jobs,
at the cell level.
Every benefit below is tied to a specific cellular process. This isn't a general "glow" serum. It's a set of molecules chosen for how they interact with mitochondrial function, cellular turnover, and the biological targets that keep skin behaving young.
02
Renewal & turnover
Normalizes epidermal tissue production, keeping the skin's renewal cycle running at the pace of a younger cell population.
03
Radiance & firmness
As cellular energy rises, so does the skin's capacity to produce collagen, maintain elasticity, and hold a healthy surface tone.
04
Longevity
A cellular-level intervention that addresses the root causes of aging, not the surface signs. The difference compounds over months, not days.
Pairs with
The system
around Serum O.
O works underneath everything. Collagen stimulation (C), cellular turnover (A), and barrier repair (M) all depend on the energy O provides. Treat it as the power supply for the rest of the routine.
Day · Brightening
Serum C
Collagen synthesis requires cellular energy. C provides the stimulus; O provides the fuel. Strongest pair for firmness and glow.
$175→
Night · Renewal
Serum A
Retinol drives turnover, which demands mitochondrial activity. Stack A at night and O by day for a full regeneration cycle.
$175→
Day & Night · Barrier
Serum M
Layer after O absorbs. The barrier M rebuilds is maintained in part by the cellular energy O supplies.
$175→
Shipping
Free standard shipping on orders over $150. Delivered worldwide from Stockholm. Full shipping details.
Returns
14 days from invoice date. Products in original packaging, refunded to the original payment method. Returns policy.
Approved & registered
Laboratory approved by Läkemedelsverket. Registered under EU Cosmetics Legislation. Never tested on animals.