01
Barrier repair
Ceramides and cholesterol esters rebuild the lipid matrix between corneocytes, the mortar that holds the outer skin layer together.
Moisture & Barrier · Day & Night
Serum M.
A nightly sanctuary for dry, sensitive, or mature skin: ceramides and skin-identical lipids that rebuild the barrier from within.
$175$5.83 / ml30 ml · Day or Night
The workRebuild the barrier. Stop the cycle.
Dry skin isn't a moisture problem. It's a barrier problem. Most moisturizers are 65–85% water plus alcohol and preservatives, which strip lipids and keep you reapplying. You put it on, it evaporates, your skin feels dry again, you reach for more. The product never fixes the problem; it is the problem.
Serum M skips the water entirely. Six ingredients · squalane, skin-identical lipids, ceramides, and a Vitamin E stabilizer · rebuild the lipid architecture of the stratum corneum directly. The barrier holds moisture on its own; your skin stops needing to be rescued.
"Babies and children don't need moisturizers. Their barrier is intact. Serum M works at that same layer."
Suitable day or night, layered over any other Transderma serum (wait a couple of minutes for the previous layer to absorb). Especially useful after Serum A at night to cushion the transitional dryness of accelerated cell turnover.
IngredientsSix ingredients. All functional.
No alcohol, no fragrance, no preservatives. Every molecule in Serum M is something your skin already recognizes: ceramides your body makes, lipids identical to your own, cholesterol esters that sit in your cell membranes. Supplementation, not substitution.
01
Squalane Skin-identical lipid base
The hydrogenated, stable form of squalene, a lipid your own skin produces. Non-comedogenic, anti-inflammatory, and completely recognized by skin tissue.
02
Isostearyl Isostearate Emollient ester
A plant-derived fatty-acid ester that smooths and softens the skin surface while supporting the lipid matrix underneath.
03
C10-30 Cholesterol/Lanosterol Esters Barrier cholesterol
Cholesterol is one of the three core lipids of the skin barrier. These esters integrate directly into the lipid bilayer and restore structural integrity.
04
Alpha-Tocopherol Vitamin E · Stabilizer & antioxidant
Protects the lipid actives from oxidation (so no preservatives are needed) and provides its own antioxidant effect on the skin.
05
Ceramide III & VI Barrier ceramides
Two of the most clinically studied ceramides for skin barrier function. Fill gaps in the lipid matrix and restore the skin's natural moisture-retention capacity.
06
Salicoyl Phytosphingosine Ceramide precursor
Converts to ceramide once inside the skin, providing a sustained rebuilding effect beyond the topical application.
How to useLast step. Any time of day.
Apply to clean, dry skin, or after another Transderma serum has absorbed. Allow one to five minutes for full absorption, then continue with your daily routine. The final step. Any time of day.
01
Clean, dry skin
Cleanse and dry. If layering, apply Serum C, A, O, or R first and let it absorb for one to five minutes.
02
A few drops of M
One to two drops across face and neck. M is concentrated; overapplication just sits on the skin.
03
Allow to absorb
Massage gently. The lipid base absorbs within one to five minutes and leaves no residue.
04
Continue routine
No additional cream needed. M can replace your moisturizer as the final step.
Standalone or stacked. Serum M can replace a moisturizer entirely. It contains no perfume, no colorant, no preservative, so it's appropriate for the most reactive or compromised skin.
What it does
Four jobs,
at the barrier.
A barrier that functions properly retains its own moisture, repels irritation, and leaves the skin feeling soft without an external film. Serum M restores function, not appearance.
02
Moisture retention
With the barrier intact, skin holds its own water without constant topping up. The feeling of "always needing more cream" goes away.
03
Softness & smoothness
Dry-skin roughness and flakiness resolve as the lipid layer reforms. Skin stops looking thirsty; it looks fed.
04
Visible plumping
Well-hydrated skin holds its shape. Fine dryness lines and crepey texture soften as the barrier rebuilds.
Pairs with
The system
around Serum M.
M is the closing layer. It complements every active in the line, especially after Serum A at night, or after Serum C or O in the morning.
Night · Renewal
Serum A
Retinol increases cell turnover, which can cause transitional dryness. M layered after A prevents that phase from ever becoming uncomfortable.
$175→
Day · Brightening
Serum C
Apply C first, wait a couple of minutes, then layer M. A complete day routine in two steps.
$175→
Day & Night · Clarity
Serum R
R targets pigmentation and scars; M keeps the skin around them calm and supported while the active does its work.
$175→
Shipping
Free standard shipping on orders over $150. Delivered worldwide from Stockholm. Full shipping details.
Returns
14 days from invoice date. Products in original packaging, refunded to the original payment method. Returns policy.
Approved & registered
Laboratory approved by Läkemedelsverket. Registered under EU Cosmetics Legislation. Never tested on animals.